When Microsoft introduced the ability to sync Windows settings across multiple devices its timing was perfect as more consumers were beginning to work with multiple devices.
The best implementation of this settings syncing feature was in Windows 8/8.1 and even synced settings to Windows RT 8/8.1 devices.
Unfortunately, the robustness of that capability has actually been reduced over the ensuing years since the release of Windows 10 back in July 2015.
However, there are still multiple settings that sync across Windows 10 based devices at the operating system level. The master control for sync settings in Windows 10 is located at Settings>Accounts>Sync your settings.
In order to stop syncing these settings across your Windows 10 devices which use the same Microsoft Account (MSA), you will need to toggle the Sync settings to off. After that you should go to your other machines which use that same MSA and turn its Sync settings option off.
Once all of those devices have had this setting turned off, you now need to remove those backed up sync settings from OneDrive. While this process is useful for simply turning off the syncing of these settings, it can also be used to remove all currently synced settings from devices and the cloud. That would allow you to start over to clean up any issues relating to syncing those settings across devices.
To remove the cloud backed up settings, you have to go to the Microsoft Account management page and then click on the Devices tab:
Scroll all the way down to the bottom of the device management page to find these four options:
Click on Cloud synced settings to get the following dialog:
To move forward just click the Clear button and you will be taken to this next dialog on OneDrive:
Here you will find additional instructions on how to stop your sync settings for Windows 8, Windows 10, and even Windows Phone. Once you are ready just click Remove. You will be asked one more time to verify that you do want to remove these settings that are stored in OneDrive.
Once they are removed you will see this result:
Now you can turn back on your sync settings if you were just clearing what was stored in the cloud. Otherwise, you are all done.