According to a post on the Office Updates blog Friday evening there are Office 2013 Click to Run users who are having issues starting their Office applications after applying the recently released June 2013 updates.

The Office Sustained Engineering team states the issue is impacting less than 1% of Office 2013 Click to Run users but they are giving it high priority so they can get a permanent fix in place for the issue.

They do give affected users a work around to get back up and running until the fix is released.

Step 1

Uninstall Office using this Fix It solution

Step 2

Reinstall Office from your My Accounts page

Source: Office Updates Blog